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Bespoke Aesthetics

Dual-Action GLP-1 / GIP

Compounded Tirzepatide in Gainesville, FL

Compounded tirzepatide works on two hormone pathways, GLP-1 and GIP, and at Bespoke it comes with a physician who knows you. Dr. Carolyn Indianos, MD, sees you, prescribes, and follows up herself. Call or text (352) 450-1004 to book.

Consultation with Dr. Indianos, MD.

Physician-ledDr. Carolyn Indianos, MD
One physicianFrom visit to follow-up
Complimentary first consultationCall or text (352) 450-1004
Gainesville, FL5010 W Newberry Rd
At a glance

Tirzepatide at Bespoke: The Short Answer

Tirzepatide is a prescription medication that activates two hormone receptors, GIP and GLP-1, which help regulate appetite and blood sugar.

At Bespoke Aesthetics in Gainesville, FL, Dr. Carolyn Indianos, MD evaluates each patient in person, reviews their medical history and labs, and prescribes compounded tirzepatide only when it is clinically appropriate. Compounded tirzepatide and FDA does not review compounded drugs for safety, effectiveness, or quality.

Physician consultation room at Bespoke Aesthetics in Gainesville, FL
Visit us

Plan your visit

Where

Bespoke Aesthetics is located at 5010 W Newberry Rd, Suite C, Gainesville, FL.

When

Clinic hours are Monday to Friday, 10:30 AM to 5 PM, and Saturday, 12 PM to 4 PM.

Book

Call (352) 450-1004 to request a consultation with Dr. Carolyn Indianos, MD.

The mechanism

Tirzepatide Mechanism, Dual GIP/GLP-1 Agonist

Tirzepatide is a weight loss medication that activates two hormone pathways: GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide 1). Semaglutide, by comparison, acts on the GLP-1 pathway only.

Its actions include increasing insulin release when blood sugar is elevated, reducing glucagon, slowing stomach emptying, and reducing appetite and food intake.

How tirzepatide acts

  • Insulin release
  • Glucagon
  • Stomach emptying
  • Appetite and food intake

These mechanisms do not establish how well any particular compounded formulation works.

What to expect

Tirzepatide Treatment and Follow-Up

  1. Visit one

    Evaluation

    Your first visit is an in-person evaluation with Dr. Indianos.

  2. Your plan

    Prescribing plan

    She reviews your history and labs and, if tirzepatide is appropriate, builds your prescribing plan.

  3. Follow-up

    Ongoing care

    After that she follows up with you herself: how you are tolerating the medication, how your weight is changing, nutrition, hydration, and anything else you need.

  4. Dosing

    Dose changes

    Any dose change is made by her based on your response, so please do not change your dose on your own.

Call or text (352) 450-1004 to book your visit.

Comparing options

Tirzepatide vs. Semaglutide: Choosing With Dr. Indianos

Tirzepatide activates GIP and GLP-1 receptors; semaglutide activates GLP-1 receptors. That difference alone does not decide which medication is right for you. Dr. Indianos considers your medical history, current medications, clinically indicated lab results, previous treatment response, goals, and cost. Any switch between medications requires a new prescribing plan.

Bright consultation room at Bespoke Aesthetics medical weight loss clinic, Gainesville FL

Not sure which one fits you? Bring your questions to your first visit.

Call or text (352) 450-1004 to book.
Safety first

Tirzepatide Side Effects & Safety

Common side effects

Common side effects include nausea, vomiting, diarrhea, and constipation. How strong they are and how long they last varies, and they may appear after a dose change. Contact Dr. Indianos for persistent or severe nausea or vomiting, or if you cannot keep fluids down.

Managing symptoms

Smaller meals and avoiding foods that worsen symptoms may help. Fluid intake and treatments for nausea or constipation should reflect your own medical conditions and medications, so discuss them with Dr. Indianos. Seek urgent care for severe or persistent abdominal pain, and emergency care for trouble breathing or swelling of the face or throat.

Serious side effects

Serious side effects, including pancreatitis, gallbladder problems, and kidney injury from dehydration, can occur. FDA-approved tirzepatide labeling carries a boxed warning for thyroid C-cell tumors seen in rats; whether tirzepatide causes these tumors in people is unknown. Tirzepatide is not used in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Dr. Indianos screens for these and other contraindications during your evaluation.

Dr. Carolyn Indianos, MD performing a physician-led aesthetic injection - Bespoke Aesthetics, Gainesville, FL
Your physician

Dr. Carolyn Indianos, MD

Founder and Medical Director, Bespoke Aesthetics

Bespoke Aesthetics is a physician-led medical clinic. Dr. Carolyn Indianos, MD practices regenerative and aesthetic medicine. She prescribes and monitors all tirzepatide protocols. All compounded medications come from U.S. state-licensed 503A pharmacies that comply with USP 797 standards. We do not use overseas compounders.

Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.

Helpful guides

Before you decide

Important information. Semaglutide and tirzepatide are prescription medications provided only after a consultation and evaluation by Dr. Indianos to determine whether treatment is appropriate for you. This page is general information and is not medical advice. Please consult Dr. Indianos about your individual situation.

Frequently Asked Questions

Common questions about treatment, protocols, and Bespoke’s clinical approach.

One manufacturer’s tirzepatide product is FDA-approved for chronic weight management. Compounded tirzepatide is a different product: it and FDA does not review compounded drugs for safety, effectiveness, or quality. Tirzepatide activates GIP and GLP-1 receptors involved in appetite and blood-sugar regulation.
The amount of weight loss, if any, varies from person to person, and no specific amount can be promised. Results from trials of FDA-approved tirzepatide do not establish the expected weight loss of the compounded product prescribed here. Dr. Indianos reviews your progress at each follow-up visit.
Tirzepatide activates GIP and GLP-1 receptors; semaglutide activates GLP-1 receptors. That difference alone does not determine which medication is appropriate for you. Dr. Indianos considers your medical history, treatment goals, current medications, and previous treatment response.
Tell Dr. Indianos which type of diabetes you have and list every medication you take. Tirzepatide can increase the risk of low blood sugar when used with insulin or medications such as sulfonylureas, so monitoring and medication adjustments may be needed. Do not change your diabetes medications on your own.
Compounded tirzepatide is generally not covered by insurance, and coverage for the FDA-approved product varies by plan. Bespoke offers clear pricing, member pricing for members, and financing through Cherry. Call or text (352) 450-1004 for current pricing.
The safety and added weight-loss benefit of combining tirzepatide with sermorelin or NAD+ IV therapy have not been established. Sermorelin stimulates the body’s own growth hormone release; it is not growth hormone. Discuss all medications and supplements with Dr. Indianos before combining treatments.
Bespoke Aesthetics serves Gainesville and 12 surrounding North Central Florida communities. Telemedicine follow-ups available; initial consultation and baseline labs require an in-person visit with Dr. Indianos.
Begin your journey

Ready to find out if tirzepatide fits your plan?

Book your visit with Dr. Indianos. She reviews your history and labs, answers your questions, and tells you plainly whether tirzepatide is a fit. Ask about member pricing and Cherry financing.

Your first consultation is complimentary

Bespoke Aesthetics
5010 W Newberry Rd, Suite C, Gainesville, FL

Where We Serve

Physician-led weight management care in Gainesville, Florida

Bespoke serves Gainesville, Haile Plantation, Tioga, Jonesville, Newberry, Alachua, High Springs, Archer, Hawthorne, Fort White, Trenton, Williston, and Ocala: physician-led care delivered at our Gainesville clinic or via Bespoke Concierge in-home service.