Microneedling with PRP Gainesville FL
Microneedling with your own platelet-rich plasma, designed to refresh tone and texture and support collagen remodeling. Personally performed by Dr. Carolyn Indianos, MD. Call or text (352) 450-1004 to book.
Consultation with Dr. Indianos, MD.
Microneedling with PRP, The “Vampire Facial,” Done Medically
Tired of acne marks, uneven texture, or skin that has lost its glow? Microneedling creates controlled micro-injuries that trigger your skin’s wound-healing cascade: new collagen, elastin, and epidermal cell turnover. Adding PRP (platelet-rich plasma) is designed to build on that response, because the growth factors in your own blood platelets support healing and the collagen response.
Popularly called the “Vampire Facial,” microneedling with PRP at Bespoke Aesthetics is a medical procedure performed by Dr. Carolyn Indianos, MD, not a spa treatment. Your blood is drawn, processed in a sterile centrifuge to isolate platelets, then applied during and after microneedling so growth factors can reach the skin through the channels created by the device.
Call or text (352) 450-1004 to book your visit. Dr. Indianos sees you in a private ground-floor suite at 5010 W Newberry Rd, Suite C in Gainesville.
What Microneedling + PRP Treats
Acne scarring
This is where microneedling has its best evidence, particularly for rolling and boxcar scars. Published studies report improvement across multiple sessions, and Dr. Indianos photographs your baseline so you can see your own progress. Ice-pick scars can be tougher, and she will tell you up front whether this or a different approach fits, before you commit to a series.
Uneven pigment
Post-inflammatory pigmentation, the kind left behind after acne or irritation, often improves as the skin remodels. Melasma needs a more careful approach because heat and aggressive treatment can aggravate it, so if that is your main concern, Dr. Indianos will tell you at your visit whether this is the right tool for you.
Fine lines and crepey skin
Collagen induction is designed to firm the dermis and soften the look of fine lines, especially around the eyes, mouth, and neck.
Texture and pore size
Smoother-feeling texture and a refined look to pores.
Stretch marks
Patients choose it for stretch marks too. It tends to be most helpful on early ones (still red or purple), and mature ones may need multiple sessions.
Hair thinning
Scalp microneedling with PRP is used for early pattern hair thinning. The evidence base is developing and this is not FDA approved for hair, and it tends to do best when started early. If you are noticing thinning, the best time to ask is now: Dr. Indianos will tell you at your visit whether you are early enough for this to be a good fit.
The Bespoke Protocol
Consultation
Dr. Indianos reviews your skin, history, medications, and goals.
PRP draw
A standard blood draw (1 to 2 vials) is processed in a sterile centrifuge to separate platelet-rich plasma from red and white blood cells.
Topical numbing
30 minutes of topical anesthetic for comfort.
Microneedling
Medical-grade device (not the “derma roller” sold at drugstores) creates precise, controlled micro-channels at depths matched to your skin and treatment goal (typically 0.5 to 2.5mm depending on area).
PRP application
Your processed PRP is applied during and after microneedling. The microchannels allow growth factors to penetrate where they would otherwise sit on the skin surface.
Recovery
Skin is pink to red for 24 to 48 hours, like a mild sunburn. Mild flaking days 3 to 5. Full recovery in 5 to 7 days.
How Many Sessions and How Often
Most indications require 3 to 6 sessions spaced 4 to 6 weeks apart for optimal results. Acne scarring may need 6 to 8 sessions. Maintenance is typically 1 to 2 sessions per year after the initial series.
Some patients notice smoother texture early, and because the deeper collagen remodeling builds over months, we plan it as a series and photograph your baseline so you can see your own progress. That remodeling continues for up to a year after your last session.
Why Choose Bespoke for Microneedling + PRP
Microneedling is offered all over town, from medspas to estheticians. Here is what you get at Bespoke:
- Physician-performed: Dr. Indianos personally performs every treatment
- Medical-grade device: not the cosmetic “derma rollers” with shallow depth
- Sterile PRP processing: certified centrifuge, sterile single-use kit, hospital-grade protocols
- Personalized depth: needle depth varies by treatment area, eyes need 0.5mm, acne scarring needs 2.0 to 2.5mm
- Layered protocols: often combined with topical growth factors, vitamin C, exosomes, or post-procedure light therapy for amplified results
Two related options: PRF, the fibrin-based preparation from your own blood, and PDGF, a targeted growth factor protocol. She will recommend the right one at your visit. Call or text (352) 450-1004 to book (Mon-Fri 10:30 AM to 5 PM, Sat 12 PM to 4 PM).
If hair thinning is your concern rather than skin texture, start with our guide to PRP and exosomes for hair loss.

Dr. Carolyn Indianos, MD
Founder and Medical Director, Bespoke Aesthetics
Bespoke Aesthetics is a physician-led medical clinic. Dr. Carolyn Indianos, MD practices regenerative and aesthetic medicine. She performs every injection personally, not delegated to nurses or estheticians.
All medications are sourced from licensed U.S. suppliers and state-licensed 503A pharmacies. We do not use overseas suppliers or unregulated products.
Frequently Asked Questions
Common questions about treatment, protocols, and Bespoke’s clinical approach.
Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.
Where We Serve
Trusted by microneedling and PRP clients across North Central Florida
Bespoke serves Gainesville, Haile Plantation, Tioga, Jonesville, Newberry, Alachua, High Springs, Archer, Hawthorne, Fort White, Trenton, Williston, and Ocala: physician-led care delivered at our Gainesville clinic or via Bespoke Concierge in-home service.
Important information. Treatments described on this page are medical procedures performed only after a consultation and evaluation by Dr. Indianos to determine whether they are appropriate for you. This page is general information and is not medical advice. Please consult Dr. Indianos about your individual situation.
These treatments are not FDA approved for the uses described here. Whether a treatment is appropriate for you is a clinical decision made at consultation.
Ready for medical-grade microneedling + PRP?
Your first consultation is complimentary.
Book your microneedling with PRP visit with Dr. Indianos. Medical-grade device, sterile PRP processing, treatment depth matched to your skin, and a physician who follows up with you herself. Call or text (352) 450-1004, Mon-Fri 10:30 AM to 5 PM or Sat 12 PM to 4 PM.
Bespoke Aesthetics
5010 W Newberry Rd, Suite C, Gainesville, FLDr. Carolyn Indianos, MD • Regenerative & Aesthetic Medicine • Gainesville, FL