PRF Gainesville FL
PRF (platelet-rich fibrin) is prepared from a sample of your own blood, right here in the office, and used in physician-led skin protocols. Dr. Indianos, MD personally performs every PRF injection. Call or text (352) 450-1004 to book.
Consultation with Dr. Indianos, MD.
PRF in Gainesville, FL
PRF (platelet-rich fibrin) is a concentrate prepared from a small sample of your own blood, spun in a centrifuge and used in select skin and regenerative protocols. If you are looking for PRF in Gainesville, FL, here is what you get at Bespoke Aesthetics: a process that is physician-led from draw to injection. Dr. Carolyn Indianos, MD personally performs every PRF injection, and the blood draw and spin are done in-office under her direct supervision, so one doctor knows your plan. PRF is offered as a standalone injectable (the under-eye area is a common request) or as an addition to microneedling. This page explains what PRF is, how it differs from PRP, and what a visit involves. Call or text (352) 450-1004 to book your PRF visit.
What PRF is
A second-generation concentrate
PRF is often described as a second-generation platelet concentrate. Like PRP, it starts with a standard blood draw.
Prepared differently
The difference is in the preparation. PRF is spun at a lower speed, for a shorter time, and without any anticoagulant. Because nothing interrupts the clotting process, the sample forms a soft fibrin matrix: a scaffold that holds platelets and a portion of your white blood cells.
A fibrin scaffold
That fibrin scaffold matters. Instead of releasing growth factors in a single early burst, the matrix is understood to release them gradually over several days as it breaks down. PRF is autologous, meaning it is prepared from your own blood, with no anticoagulant and no added preservatives.
PRF vs PRP: what actually differs
Patients often ask whether PRF is just a rebranded version of PRP. It is not. Both are platelet concentrates made from your own blood, but the preparation method changes how the final product looks and behaves.
PRF (platelet-rich fibrin)
- Spin speedLower speed, shorter spin
- AnticoagulantNone
- Growth-factor releaseGradual, over several days as the fibrin matrix breaks down
- TextureSoft gel that begins to set after preparation
PRP (platelet-rich plasma)
- Spin speedHigher speed, often two spin cycles
- AnticoagulantAdded to keep the sample liquid
- Growth-factor releaseFaster, with an early peak
- TextureLiquid, remains injectable
Neither preparation is better across the board; they are simply suited to different protocols. Dr. Indianos offers both. You can read about the plasma version on our PRP page, and about microneedling with PRP as a combined treatment. Which preparation fits your situation is a clinical decision, and candidacy is determined at your consultation.
How Dr. Indianos uses PRF at Bespoke
Bespoke Aesthetics offers PRF in Gainesville, FL in two formats.
Standalone PRF injections
PRF can be injected on its own, without microneedling. The under-eye area is the most frequent request; the soft, slowly setting texture is one reason physicians select PRF for delicate, thin-skinned areas. It is also used in protocols designed to support overall skin quality.
PRF with microneedling
PRF can be applied during a microneedling session, where the channels created by the device allow the preparation to reach the skin directly. If you are weighing this against microneedling with PRP, that comparison is exactly the kind of question your consultation is for.
Within our biostimulators category, PRF sits alongside PRP and other biostimulator options. Each is used in different protocols, and none of them is a one-size answer. Candidacy is determined at your consultation.
What a PRF visit looks like
- Consultation
Start with a conversation
Every PRF patient starts with a conversation with Dr. Indianos. She reviews your health history, looks at the areas you want addressed, and tells you straight whether PRF is a good fit or whether another protocol suits you better. Your first consultation is complimentary.
- Treatment
Blood draw and spin
Treatment begins with a blood draw, like routine lab work. Your sample is spun on-site while you wait, then prepared and either injected or applied with microneedling.
- Going home
Aftercare
You leave with clear aftercare instructions, and because PRF is drawn and prepared fresh at each visit, nothing is ordered ahead and nothing is stored between appointments.
Dr. Carolyn Indianos, MD
Founder and Medical Director, Bespoke Aesthetics
Dr. Carolyn Indianos, MD holds an active Florida medical license and practices regenerative and aesthetic medicine at Bespoke Aesthetics in Gainesville. She personally performs every PRF injection and follows up with you herself.
Bespoke Aesthetics is a physician-led medical clinic. Dr. Carolyn Indianos, MD practices regenerative and aesthetic medicine. She supervises every treatment. We do not use overseas compounders or unregulated suppliers.
Location and Hours
Bespoke Aesthetics is located at 5010 W Newberry Rd, Suite C, Gainesville, FL 32607. We see patients by appointment. Call (352) 450-1004 to schedule, or reach us through the contact page.
This page is for informational purposes only and does not constitute medical advice. All treatment decisions are made individually between you and Dr. Indianos after a physician evaluation. No specific outcome is guaranteed.
Frequently Asked Questions
Common questions about treatment, protocols, and Bespoke’s clinical approach.
Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.
Ready for a physician-led PRF plan?
If you have been researching PRF and want a physician-led process from draw to injection, book your visit. Your first consultation is complimentary. Call or text (352) 450-1004, Mon-Fri 10:30 AM to 5 PM or Sat 12 PM to 4 PM.
Related treatments in Gainesville: PRP · Microneedling + PRP · Biostimulators · Exosomes
Bespoke Aesthetics
5010 W Newberry Rd, Suite C, Gainesville, FLDr. Carolyn Indianos, MD • Regenerative & Aesthetic Medicine • Gainesville, FL