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Bespoke Aesthetics

Salmon DNA Skin Regeneration

Polynucleotide Therapy Gainesville FL

Polynucleotide therapy uses purified salmon DNA fragments, with the goal of supporting your skin’s own repair for better hydration, texture, and elasticity. Dr. Indianos, MD injects it herself. Call or text (352) 450-1004 to book.

Consultation with Dr. Indianos, MD.

Physician-ledDr. Carolyn Indianos, MD
Private suiteGround-floor suite
Complimentary first consultationCall or text (352) 450-1004
Gainesville, FL5010 W Newberry Rd
Regenerative skin therapy

What Polynucleotide Therapy Is

If your skin looks dull, thin, or tired and you want it to look healthier without adding volume, polynucleotide therapy is a regenerative option to ask Dr. Indianos about. It uses purified polynucleotides, chains of DNA fragments typically derived from salmon, intended to support the skin’s own repair environment, with the goal of improved hydration, texture, and elasticity over a short course of treatments.

Clinical preparation tray in a treatment room at Bespoke Aesthetics, Gainesville FL
Good to know

Physician discretion, openly stated

Polynucleotide injectables do not have FDA approval for aesthetic use in the United States; this treatment is offered as a regenerative option at the physician’s discretion, and Dr. Indianos reviews candidacy individually at consultation.

How it works

How polynucleotide therapy works

Purified DNA fragments

Polynucleotides are highly purified DNA fragments. Delivered into the skin in small amounts, they are intended to support the skin’s natural repair processes and hydration, with the goal of better overall skin quality and resilience.

A gradual change

The change is gradual. Treatment is typically a short series of sessions spaced a few weeks apart, and temporary redness, swelling, or small bumps at the injection sites generally settle within a few days.

Neither filler nor neurotoxin

It is not designed to add structural volume the way a filler does, and it does not relax muscles the way a neurotoxin does.

This treatment is regenerative and provided at physician discretion; Call or text (352) 450-1004 to book your visit.

Dr. Carolyn Indianos, MD, at work in the Bespoke Aesthetics treatment room
Your physician

Dr. Carolyn Indianos, MD

Founder and Medical Director, Bespoke Aesthetics

At Bespoke Aesthetics, polynucleotide therapy is administered personally by Dr. Carolyn Indianos, MD.

Bespoke Aesthetics is a physician-led medical clinic. Dr. Carolyn Indianos, MD practices regenerative and aesthetic medicine.

She performs every injection personally, not delegated to nurses or estheticians.

Our standard

All medications are sourced from licensed U.S. suppliers and state-licensed 503A pharmacies. We do not use overseas suppliers or unregulated products.

Frequently Asked Questions

Common questions about treatment, protocols, and Bespoke’s clinical approach.

Highly purified DNA fragments, most often derived from salmon and refined for clinical use.

Neither. They are not designed to add structural volume like a dermal filler, and they do not relax muscles like a neurotoxin. Polynucleotide therapy is a regenerative treatment focused on skin quality.

Injectable polynucleotides do not have FDA approval for aesthetic use in the United States. Bespoke offers the treatment as a regenerative option at the physician’s discretion; Dr. Indianos reviews your candidacy at consultation.

It is used with the goal of improving skin hydration, texture, and elasticity. Results are gradual and vary from person to person.

Temporary redness, swelling, or small bumps at the injection sites are common and generally settle within a few days.

Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.

Begin your journey

Ready for physician-injected Polynucleotide Therapy?

Your first consultation is complimentary.

Book your visit with Dr. Indianos. Conservative dosing, careful technique, and a physician who injects you herself and follows up with you personally. Call or text (352) 450-1004, Mon-Fri 10:30 AM to 5 PM or Sat 12 PM to 4 PM.

Bespoke Aesthetics
5010 W Newberry Rd, Suite C, Gainesville, FLDr. Carolyn Indianos, MD • Regenerative & Aesthetic Medicine • Gainesville, FL