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Bespoke Aesthetics

Physician-Led GLP-1 Weight Loss

Compounded Semaglutide in Gainesville, FL

Compounded semaglutide prescribed by Dr. Carolyn Indianos, MD, with a real visit, baseline labs, and follow-up from the same physician at every step. Call or text (352) 450-1004 to book.

Consultation with Dr. Indianos, MD.

Physician-ledDr. Carolyn Indianos, MD
One physicianFrom visit to follow-up
Complimentary first consultationCall or text (352) 450-1004
Gainesville, FL5010 W Newberry Rd
The mechanism

How Semaglutide Works, GLP-1 Receptor Agonist Mechanism

Semaglutide is a GLP-1 receptor agonist, a synthetic peptide that mimics glucagon-like peptide 1, a hormone that regulates blood sugar and appetite.

Consultation corner at Bespoke Aesthetics medical weight loss clinic, Gainesville FL
How it works

What semaglutide does

Fullness and hunger

When you inject semaglutide, it activates GLP-1 receptors in your brain, signaling fullness and reducing hunger.

After meals

Simultaneously, it slows gastric emptying, extending the feeling of satiety after meals.

Nutrition and movement

Combined with light exercise and balanced nutrition, this can support a sustained calorie deficit, the foundation of healthy weight loss.

Semaglutide reduces appetite and slows stomach emptying; effects differ by person.

Your first visit

One physician, start to finish

At Bespoke Aesthetics, Dr. Indianos prescribes compounded semaglutide, a GLP-1 receptor agonist, and stays with you from the first visit on: baseline labs, injection training so you feel confident at home, a dose plan she adjusts as you go, and follow-up by telemedicine or in person. You see one physician who knows your history, not a different provider every month.

Your first visit is unhurried. Dr. Indianos reviews your history, talks through your goals, and explains how the medication works and what to expect, so you leave knowing the plan. Visits take place in our private ground-floor suite with easy parking. Call or text (352) 450-1004 to book.

Physician consultation room at Bespoke Aesthetics in Gainesville, FL
Comparing options

Semaglutide vs. Tirzepatide, Which Is Right for You?

The brand-name versions are FDA-approved for chronic weight management. The key difference is mechanism of action.

Semaglutide (GLP-1 agonist): single hormone mechanism (appetite suppression); longer market history.

Tirzepatide (GIP/GLP-1 agonist): dual hormone mechanism (appetite plus glucose regulation); newer.

Dr. Indianos reviews your baseline labs (fasting insulin, glucose, A1C, lipid panel) and health history to recommend the medication best suited to your individual metabolism. If your response changes over time, she may adjust your dose or discuss a different medication.

Not sure which medication fits? That is what the first visit is for.

Your first visit
Dr. Carolyn Indianos, MD, at work in the Bespoke Aesthetics treatment room
Your physician

Dr. Carolyn Indianos, MD

Founder and Medical Director, Bespoke Aesthetics

Bespoke Aesthetics is a physician-led medical clinic. Dr. Carolyn Indianos, MD practices regenerative and aesthetic medicine. She prescribes and monitors all semaglutide protocols. All compounded medications are dispensed by U.S. state-licensed 503A pharmacies that comply with USP 797 standards. We do not use overseas compounders or unregulated suppliers.

Call or text (352) 450-1004 to book with Dr. Indianos.

Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.

Good to know

Important information

Bespoke Aesthetics prescribes compounded semaglutide in Gainesville, FL, at 5010 W Newberry Rd, Suite C. Compounded semaglutide and FDA does not review compounded drugs for safety, effectiveness, or quality. Dr. Carolyn Indianos, MD decides whether treatment is appropriate after a consultation. Clinic hours are Monday to Friday, 10:30 AM to 5 PM, and Saturday, 12 PM to 4 PM. Call (352) 450-1004 to request a consultation.

Important information. Semaglutide and tirzepatide are prescription medications provided only after a consultation and evaluation by Dr. Indianos to determine whether treatment is appropriate for you. This page is general information and is not medical advice. Please consult Dr. Indianos about your individual situation.

Helpful guides

Before you decide

Frequently Asked Questions

Common questions about treatment, protocols, and Bespoke’s clinical approach.

GLP-1 (glucagon-like peptide 1) is a natural hormone that regulates blood sugar and appetite. Semaglutide mimics GLP-1, activating hunger-suppression pathways in your brain, which can reduce appetite and calorie intake.
How much weight people lose varies widely and depends on many factors. Dr. Indianos discusses realistic, individual goals at your visit. Compounded semaglutide has not been studied in the clinical trials of FDA-approved semaglutide products.
Appetite often returns, and some of the weight can come back, when semaglutide is stopped. That is why Dr. Indianos plans the next step with you before you get there. Together you decide whether to continue, adjust your dose, or step down, with follow-up visits along the way.
Semaglutide (GLP-1) and tirzepatide (dual GIP/GLP-1) differ in mechanism. Dr. Indianos recommends the medication best suited to your labs and metabolism.
Compounded semaglutide is generally not covered by insurance, and coverage for brand-name products varies by plan. Bespoke offers clear pricing, member pricing for members, and financing through Cherry. Call or text (352) 450-1004 for current pricing.
Bespoke Aesthetics serves Gainesville and 13 surrounding cities (Newberry, Alachua, Jonesville, Tioga, Haile Plantation, High Springs, Ocala, and more) within 15–45 minute drive time. Telemedicine follow-ups available; initial consultation and labs require an in-person visit.
Begin your journey

Ready to start GLP-1 weight loss?

Book your baseline visit with Dr. Indianos. You will meet the physician who prescribes and follows your plan, go over your health history and labs together, and leave with clear next steps. Ask about member pricing and Cherry financing.

Your first consultation is complimentary

Bespoke Aesthetics
5010 W Newberry Rd, Suite C, Gainesville, FL

Where We Serve

Trusted by semaglutide weight loss clients across North Central Florida

Bespoke serves Gainesville, Haile Plantation, Tioga, Jonesville, Newberry, Alachua, High Springs, Archer, Hawthorne, Fort White, Trenton, Williston, and Ocala: physician-led care delivered at our Gainesville clinic or via Bespoke Concierge in-home service.

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