Myers' Cocktail IV Gainesville FL

What is a Myers Cocktail?

The Myers cocktail was developed in the 1970s by Dr. John Myers in Baltimore as an intravenous combination of B vitamins, vitamin C, magnesium, and calcium. Decades later it remains the most-requested IV in functional medicine for general wellness, immune support, energy, and recovery.

The rationale is straightforward: some people are genuinely low in these micronutrients because of diet, stress, illness, or absorption problems, and repletion helps those people. Oral supplements have to get through the gut, and how much actually makes it into circulation varies by nutrient and by person. IV skips that step, so what goes into the bag reaches your bloodstream directly. It follows that if you are not low to begin with, there is less reason to expect much. Labs tell us which you are.

What’s in a Bespoke Myers Cocktail

• Vitamin B-complex: B1 (thiamine), B2 (riboflavin), B3 (niacinamide), B5 (pantothenic acid), B6 (pyridoxine), B12 (methylcobalamin) — energy metabolism, nerve function, neurotransmitter synthesis
• Vitamin C: 500–1500 mg — antioxidant, immune support, collagen synthesis, iron absorption co-factor
• Magnesium: 1–2 g — muscle relaxation, energy production (Krebs cycle), stress reduction, sleep quality, blood pressure regulation
• Calcium: 1–2 g — bone health, muscle function, nerve transmission

Custom modifications: add high-dose vitamin C for immune-focused protocols, glutathione for antioxidant support, taurine for cardiovascular support, manganese for joint health.

The range below reflects what Dr. Indianos typically prescribes based on patient response. It is not a recommendation for self-treatment: your exact dose is determined only after an in-person evaluation with Dr. Indianos.

When Patients Use Myers Cocktail

General wellness: baseline micronutrient repletion when diet, stress, or absorption is suboptimal.

Athletic recovery: magnesium accelerates muscle recovery, B vitamins support energy metabolism. Pre/post-event use is common.

After being sick. Appetite and fluid intake usually drop during an illness, and people often feel behind for a while afterward. Some patients use this drip in that window. It is hydration and micronutrients, not an antiviral, and it will not shorten an infection you currently have.

Persistent fatigue. Fatigue that does not resolve with sleep deserves a workup, not an IV. Thyroid, iron, B12, sleep apnea, and depression are all more likely explanations than a micronutrient gap. If your labs show an actual deficiency, repletion makes sense. If they do not, this drip is not the answer, and Dr. Indianos will tell you that.

Stress and anxiety: magnesium has anxiolytic effects. B vitamins support neurotransmitter balance.

Migraine. Some patients ask about this. Magnesium has been studied for migraine, and the literature is genuinely mixed, with the better-quality evidence sitting on oral magnesium for prevention rather than on IV infusions in a wellness setting. We are not going to present this drip as a migraine treatment. If you get migraines, that belongs with a neurologist, and Dr. Indianos will say so.

Pre/post-event support: wedding, athletic competition, public speaking, travel — many patients use Myers as a preparation/recovery tool.

Myers Cocktail Protocol at Bespoke

Session length: 30–45 minute infusion in our IV lounge.

Frequency: weekly for 4–6 weeks for active repletion, then every 2–4 weeks for maintenance. Some patients prefer monthly.

What you’ll feel: warmth at the infusion site, improved energy, often a calming effect from magnesium, sometimes a flush from B vitamins. Most patients feel an energy and clarity boost within 24–48 hours.

Safety: Myers cocktail is well-tolerated in most patients. Contraindications include G6PD deficiency (high-dose vitamin C concern) and severe kidney disease (magnesium concern). Dr. Indianos screens new patients.

Stacking options: commonly combined with NAD+ IV, glutathione, or high-dose vitamin C for synergistic protocols. Dr. Indianos personalizes the stack.

Some preparations offered here are compounded and are not FDA approved. Compounded medications are prepared by state-licensed 503A pharmacies and are not reviewed by the FDA for safety, effectiveness, or quality before marketing. These services are not a treatment for any medical condition. Individual results vary, and no outcome is guaranteed.