PDGF Gainesville FL
Growth factor skin treatments with microneedling, designed to support skin quality under physician-led care.
Consultation with Dr. Indianos, MD.
PDGF, short for platelet-derived growth factor, is one of the signals your body releases to begin tissue repair. At Bespoke Aesthetics, Dr. Carolyn Indianos, MD offers PDGF with microneedling and in select skin protocols designed to support skin quality. If you have been searching for PDGF Gainesville FL treatment options, most of what you will find online is written for researchers, not patients. This page explains what PDGF is, how it compares to PRP, PRF, and exosomes, and what a visit here looks like. Candidacy is determined at your consultation.
What Is PDGF?
Platelet-derived growth factor is a signaling protein your platelets carry to injury sites. When tissue is damaged, platelets release PDGF, which calls fibroblasts (the cells that produce collagen) into the area and plays a role in forming new blood vessels. It is one of the earliest and best-studied molecules in the wound-healing cascade.
In aesthetic medicine, PDGF is supplied as a prepared solution at a labeled concentration, rather than being drawn from your blood on the day of treatment. That is the practical distinction between PDGF preparations and autologous platelet treatments such as PRP: with PDGF, the growth factor content is stated on the preparation’s label rather than depending on your platelet count that morning. Because many of these preparations are compounded, their potency and consistency are not verified by the FDA.
Two points worth stating plainly. First, PDGF preparations used for aesthetic skin treatments are not FDA approved for skin rejuvenation, and some are compounded. Second, PDGF carries its own risks, separate from the microneedling used to deliver it: possible irritation at the treatment area and, less commonly, an allergic reaction to the preparation. The safety and effectiveness of PDGF preparations for skin rejuvenation have not been established by the FDA. Dr. Indianos reviews the risks, benefits, and alternatives with you at your consultation before any treatment is scheduled.
How We Use PDGF at Bespoke Aesthetics
Dr. Indianos holds an active Florida medical license and practices regenerative and aesthetic medicine. She offers PDGF in two settings:
- With microneedling. The PDGF solution is applied to the skin during and immediately after microneedling, while the microchannels created by the treatment are still open. The pairing is designed to support skin texture and overall skin quality.
- In select skin protocols. For some patients, PDGF is used as part of a broader plan alongside options from our collagen biostimulation menu, such as Sculptra or polynucleotides. Which combination makes sense, if any, is determined at your consultation.
For patients researching PDGF Gainesville FL providers, the difference at a physician-led practice is that treatment selection starts with your skin and your health history, not with a menu. If a different option, or no treatment at all, is the better answer, that is what Dr. Indianos will tell you.
PDGF vs PRP vs PRF vs Exosomes
These four are often mentioned together, and they do overlap: all are used with microneedling, and all are chosen to support skin quality. They differ in where they come from, what they contain, and how they are delivered.
| Treatment | Source | What it contains | How it is delivered |
|---|---|---|---|
| PDGF | Prepared solution supplied at a labeled concentration (some preparations are compounded) | A single growth factor (platelet-derived growth factor), extensively studied in wound healing | Applied topically with microneedling; used in select skin protocols |
| PRP (platelet-rich plasma) | Your own blood, drawn and spun the same visit | Concentrated platelets in plasma carrying a broad mix of growth factors | Injected, or applied with microneedling |
| PRF (platelet-rich fibrin) | Your own blood, spun at a lower speed without anticoagulant | Platelets and white cells held in a fibrin matrix that releases growth factors gradually | Injected, or applied with microneedling |
| Exosomes | Laboratory-derived from cell cultures | Extracellular vesicles carrying proteins, lipids, and signaling molecules | Applied topically, most often immediately after microneedling |
Regulatory note: PDGF preparations used for aesthetic skin treatments are not FDA approved, and the potency and consistency of compounded preparations are not FDA-verified. The FDA has stated there are no FDA-approved exosome products. Dr. Indianos reviews the regulatory status of any option she recommends before treatment is scheduled.
None of these options is automatically better than the others. The right choice depends on your skin, your goals, whether you prefer a preparation made from your own blood, and your budget. For patients comparing PDGF Gainesville FL options against microneedling with PRP or exosomes, that comparison is exactly what the consultation is for.
What Your Visit Looks Like
Every PDGF plan at our Gainesville office begins with a private consultation with Dr. Indianos. She examines your skin, reviews your health history and goals, and tells you whether PDGF, another option, or a combination is the appropriate plan. The consultation is complimentary.
On a treatment day, your skin is cleansed and numbed, microneedling is performed, and the PDGF solution is applied. Appointments are unhurried and by appointment only. Temporary redness is common after microneedling, and Dr. Indianos provides aftercare guidance before you leave. Individual results vary, and the number of sessions in your plan is set at your consultation.
Ongoing skin plans can pair with our membership. Ask about it at your visit.
Location and Hours
Bespoke Aesthetics
5010 W Newberry Rd, Suite C
Gainesville, FL 32607
(352) 450-1004
By appointment
We see patients from Gainesville and the surrounding North Central Florida communities. Meet Dr. Carolyn Indianos, MD.
Regulatory note: PDGF preparations used for aesthetic skin treatments are not FDA approved, and the potency and consistency of compounded preparations are not FDA-verified. The FDA has stated there are no FDA-approved exosome products. Dr. Indianos reviews the regulatory status of any option she recommends before treatment is scheduled.
This page is for informational purposes only and does not constitute medical advice. All treatment decisions are made individually between you and Dr. Indianos after a physician evaluation. Results vary by patient. No specific outcome is guaranteed.
Some preparations offered here are compounded and are not FDA approved. Compounded medications are prepared by licensed compounding pharmacies or outsourcing facilities and are not evaluated by the FDA for safety and effectiveness before marketing. Individual results vary, and no outcome is guaranteed.
PDGF and hair
Growth factor treatments are one of the options Dr. Indianos may discuss for thinning hair, alongside PRP and scalp microneedling with PRP. Which one suits you, if any, depends on what is actually causing the thinning, which is why hair care here starts with an evaluation rather than a product. See hair restoration for how that evaluation works, and our evidence guide to PRP and exosomes for hair loss for what the research supports.
Frequently Asked Questions
Common questions about treatment, protocols, and Bespoke’s clinical approach.
Medically reviewed by Dr. Carolyn Indianos, MD, Founder and Medical Director, Bespoke Aesthetics.
BEGIN YOUR JOURNEY
Ready to explore growth factor skin care?
If you are weighing PDGF against PRP, PRF, or exosomes, the fastest way to a clear answer is a conversation with the physician who directs your treatment plan. Bespoke Aesthetics is a physician-led practice, and every plan starts with Dr. Indianos. The consultation is complimentary.
Dr. Carolyn Indianos, MD • Regenerative & Aesthetic Medicine • Gainesville, FL
Related treatments in Gainesville: Microneedling · PRP · PRF · Exosomes